Prof. Dr. Mohd. Zobir Hussein
Programme Manager for Nanomaterials
Materials Synthesis and Characterization Laboratory (MSCL) , Institute of Advanced Technology (ITMA),
Universiti Putra Malaysia (UPM), 43400, UPM,
Serdang , Selangor , MALAYSIA.
Tel: +06-8946 8092(O)
Fax: +06-8946 7006
Prof. Dr. Mohd Zobir Hussein obtained his PhD degree from University of Reading, U.K. and spent his postdoctoral/research attachments on nanoscience and nanomaterials and their applications at various laboratories; University of Southampton, U.K., Pennsylvania State University, USA, Victoria University of Wellington, New Zealand and University of Western Australia. He is currently the programme manager for nanomaterials at the Materials Synthesis and Characterization Laboratory, Institute of Advanced Technology (ITMA), UPM. He and his research group focusing their research works on nanomedicine, especially for theranostics delivery systems, nanomaterials for thermal energy storage and agronanochemicals. His research interests are in the design, synthesis and applications to improve drug and diagnostic agents’ bioavailability and efficacy by nanotechnology platforms. Nanomaterials, such as layered hydroxides, magnetic nanoparticles, carbon nanostructures including graphene and graphene oxide and polymers are among nanovectors used for theranostics delivery systems with controlled release properties. Together with other collaborators, his group also works on strategies to increase therapeutic and diagnostics effect for anti-cancer and anti-tuberculosis drugs, as well as other diseases via in vitro and in vivo studies. His group also works on nanomaterials for green, comfortable building applications by core-shell nano-encapsulation approach for thermal energy storage using phase change materials as the core and polymer or activated carbon pores as the shape stabilizing agents. In addition, his group also works on agronanochemicals, especially for controlling palm oil Ganoderma diseases and non-pesticide insect control.
Title : ” Nanoscience and Nanotechnology for Medicine and Energy: Opportunities and Challenges “
The use of nanoscience and nanotechnology in medicine or energy, the so-called nanomedicine or nanoenergy, respectively could revolutionize the current technology based on the “bulk” materials. Various types of nanomaterials can be used as the hosts for various guests such as therapeutic drugs, contrast agent, DNA, phase change materials, etc. As a result, various supramolecular nanoconstructs of “host-guest” type can be designed and synthesized for various applications in nanomedicine and nanoenergy. The nanoconstruct could be also used as a vector of the guest to deliver it directly to the target cells. This will increase the efficacy of the drug to the target cells, reduce the drug dosage and minimized possible side effects. Iron oxide nanoparticles, multi-wall carbon nanotubes, layered hydroxides and graphene oxide loaded with drug shows promising physico-chemical properties with controlled release capability. Optimization of the synthesis parameters to obtain phase-pure nanodelivery systems with high drug loading is important, so that the release of the drugs from the nanostructures is of controlled manner. As a result, they can be used as a smart drug delivery system with controlled release properties. Layered hydroxide and graphene oxide nanocomposites doped with gadolinium/gold nanoparticles can be used for magnetic resonance imaging (MRI), leading towards multimodal nanotheranostics agent for imaging of cancer and drug delivery systems. In addition, core-shell, nano-encapsulated phase change materials (PCM) could control temperature fluctuation which is useful for green building application. Similarly, micro- and mesoporous activated carbon derived from precursors can be exploited as frameworks to encapsulate PCM for the formation of shape-stabilised PCM for the same purposes. These show that nanoscience and nanotechnology opened up a lot of opportunities to serve various applications with superior properties compared to their bulk counterparts. However, due to their multidisciplinary in nature, these areas of research are challenging but rewarding.